methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase,

Symbol

Mthfd1 (may also be known as: Dcs, Mthfd)

Organism

Mouse

Orthologs

SymbolSpecies
pug Drosophila melanogaster
mthfd1b Danio rerio
MTHFD1 Homo sapiens
Mthfd1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1564 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase Molecular lung Mouse Mthfd1 3.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000105 histidine biosynthetic process biological_process
GO:0006164 purine nucleotide biosynthetic process biological_process
GO:0006548 histidine catabolic process biological_process
GO:0006730 one-carbon metabolic process biological_process
GO:0008152 metabolic process biological_process
GO:0008652 cellular amino acid biosynthetic process biological_process
GO:0009086 methionine biosynthetic process biological_process
GO:0009396 folic acid-containing compound biosynthetic process biological_process
GO:0005737 cytoplasm cellular_component
GO:0005739 mitochondrion cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0003824 catalytic activity molecular_function
GO:0004329 formate-tetrahydrofolate ligase activity molecular_function
GO:0004477 methenyltetrahydrofolate cyclohydrolase activity molecular_function
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0016155 formyltetrahydrofolate dehydrogenase activity molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0016874 ligase activity molecular_function