Fc fragment of IgG, high affinity Ib, receptor (CD64)

Symbol

FCGR1B (may also be known as: None)

Organism

Human

Description

Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2139 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular temporal lobe Human FCGR1B 166.0% Increase Gene Expression Level
DAA2141 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular hippocampus Human FCGR1B 434.2% Increase Gene Expression Level
DAA2143 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular parietal lobe Human FCGR1B 225.5% Increase Gene Expression Level
DAA2145 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular frontal lobe Human FCGR1B 170.4% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I biological_process
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent biological_process
GO:0006955 immune response biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I biological_process
GO:0060333 interferon-gamma-mediated signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0030669 clathrin-coated endocytic vesicle membrane cellular_component
GO:0031901 early endosome membrane cellular_component
GO:0004872 receptor activity molecular_function
GO:0019763 immunoglobulin receptor activity molecular_function
GO:0019864 IgG binding molecular_function