acyl-CoA thioesterase 11


ACOT11 (may also be known as: None)




This gene encodes a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]


acot11b Danio rerio
Acot11 Mus musculus
Acot11 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006631 fatty acid metabolic process biological_process
GO:0009266 response to temperature stimulus biological_process
GO:0009409 response to cold biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0005622 intracellular cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004091 carboxylesterase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0047617 acyl-CoA hydrolase activity molecular_function