interleukin 6 (interferon, beta 2)

Symbol

IL6

Organism

Human

Orthologs

SymbolSpecies
Il6 Mus musculus
Il6 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0001781 neutrophil apoptosis biological_process
GO:0002384 hepatic immune response biological_process
GO:0002446 neutrophil mediated immunity biological_process
GO:0002548 monocyte chemotaxis biological_process
GO:0002675 positive regulation of acute inflammatory response biological_process
GO:0002690 positive regulation of leukocyte chemotaxis biological_process
GO:0006469 negative regulation of protein kinase activity biological_process
GO:0006953 acute-phase response biological_process
GO:0006954 inflammatory response biological_process
GO:0006955 immune response biological_process
GO:0006959 humoral immune response biological_process
GO:0007568 aging biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0008285 negative regulation of cell proliferation biological_process
GO:0008360 regulation of cell shape biological_process
GO:0009408 response to heat biological_process
GO:0009409 response to cold biological_process
GO:0009611 response to wounding biological_process
GO:0009612 response to mechanical stimulus biological_process
GO:0009617 response to bacterium biological_process
GO:0010574 regulation of vascular endothelial growth factor production biological_process
GO:0010888 negative regulation of lipid storage biological_process
GO:0014070 response to organic cyclic compound biological_process
GO:0016049 cell growth biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0030168 platelet activation biological_process
GO:0031000 response to caffeine biological_process
GO:0031018 endocrine pancreas development biological_process
GO:0031175 neuron projection development biological_process
GO:0031667 response to nutrient levels biological_process
GO:0032494 response to peptidoglycan biological_process
GO:0032496 response to lipopolysaccharide biological_process
GO:0032722 positive regulation of chemokine production biological_process
GO:0032755 positive regulation of interleukin-6 production biological_process
GO:0032868 response to insulin stimulus biological_process
GO:0032966 negative regulation of collagen biosynthetic process biological_process
GO:0033138 positive regulation of peptidyl-serine phosphorylation biological_process
GO:0033160 positive regulation of protein import into nucleus, translocation biological_process
GO:0034097 response to cytokine stimulus biological_process
GO:0042102 positive regulation of T cell proliferation biological_process
GO:0042110 T cell activation biological_process
GO:0042493 response to drug biological_process
GO:0042517 positive regulation of tyrosine phosphorylation of Stat3 protein biological_process
GO:0042832 defense response to protozoan biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process biological_process
GO:0043200 response to amino acid stimulus biological_process
GO:0043410 positive regulation of MAPKKK cascade biological_process
GO:0043526 neuroprotection biological_process
GO:0045079 negative regulation of chemokine biosynthetic process biological_process
GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep biological_process
GO:0045429 positive regulation of nitric oxide biosynthetic process biological_process
GO:0045454 cell redox homeostasis biological_process
GO:0045599 negative regulation of fat cell differentiation biological_process
GO:0045630 positive regulation of T-helper 2 cell differentiation biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0045669 positive regulation of osteoblast differentiation biological_process
GO:0045721 negative regulation of gluconeogenesis biological_process
GO:0045727 positive regulation of translation biological_process
GO:0045740 positive regulation of DNA replication biological_process
GO:0045765 regulation of angiogenesis biological_process
GO:0045768 positive regulation of anti-apoptosis biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0046427 positive regulation of JAK-STAT cascade biological_process
GO:0046677 response to antibiotic biological_process
GO:0046716 muscle cell homeostasis biological_process
GO:0046849 bone remodeling biological_process
GO:0046888 negative regulation of hormone secretion biological_process
GO:0048635 negative regulation of muscle organ development biological_process
GO:0048661 positive regulation of smooth muscle cell proliferation biological_process
GO:0050679 positive regulation of epithelial cell proliferation biological_process
GO:0050710 negative regulation of cytokine secretion biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0050829 defense response to Gram-negative bacterium biological_process
GO:0050830 defense response to Gram-positive bacterium biological_process
GO:0050871 positive regulation of B cell activation biological_process
GO:0051024 positive regulation of immunoglobulin secretion biological_process
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0051384 response to glucocorticoid stimulus biological_process
GO:0051592 response to calcium ion biological_process
GO:0051602 response to electrical stimulus biological_process
GO:0051607 defense response to virus biological_process
GO:0051897 positive regulation of protein kinase B signaling cascade biological_process
GO:0051971 positive regulation of transmission of nerve impulse biological_process
GO:0060445 branching involved in salivary gland morphogenesis biological_process
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis biological_process
GO:0070091 glucagon secretion biological_process
GO:0070102 interleukin-6-mediated signaling pathway biological_process
GO:0070301 cellular response to hydrogen peroxide biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:2000366 positive regulation of STAT protein import into nucleus biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005896 interleukin-6 receptor complex cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0005125 cytokine activity molecular_function
GO:0005138 interleukin-6 receptor binding molecular_function
GO:0008083 growth factor activity molecular_function