chemokine (C-X-C motif) ligand 5

Symbol

CXCL5 (may also be known as: None)

Organism

Human

Description

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion. [provided by RefSeq, May 2013]

Orthologs

SymbolSpecies
Cxcl5 Mus musculus
Cxcl5 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2299 chemokine (C-X-C motif) ligand 5 increases with age Molecular hippocampus Human CXCL5 64.9% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006935 chemotaxis biological_process
GO:0006955 immune response biological_process
GO:0007165 signal transduction biological_process
GO:0007267 cell-cell signaling biological_process
GO:0008284 positive regulation of cell proliferation biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0008009 chemokine activity molecular_function