DAA2451 |
serine (or cysteine) proteinase inhibitor; clade A (alpha-1 antiproteinase; antitrypsin); member 12 increases with age |
Molecular |
mesenchymal stem cell |
Human |
SERPINA12 |
52.7% Increase DNA Methylation |
|
DAA2432 |
sperm associated antigen 7 decreases with age |
Molecular |
mesenchymal stem cell |
Human |
SPAG7 |
26.2% Decrease DNA Methylation |
|
DAA2438 |
syncoilin; intermediate filament 1 increases with age |
Molecular |
mesenchymal stem cell |
Human |
SYNC |
21.4% Increase DNA Methylation |
|
DAA2457 |
tumor necrosis factor receptor superfamily; member 17 increases with age |
Molecular |
mesenchymal stem cell |
Human |
TNFRSF17 |
18.8% Increase DNA Methylation |
|
DAA677 |
Proportion of apoptotic cells may be increased |
Physiological |
mesenchymal stem cell |
Human |
TP53 |
— |
|
DAA2459 |
transmembrane 4 superfamily member 3 increases with age |
Molecular |
mesenchymal stem cell |
Human |
TSPAN8 |
36.4% Increase DNA Methylation |
|
DAA2440 |
WNT1 inducible signaling pathway protein 2 precursor decreases with age |
Molecular |
mesenchymal stem cell |
Human |
WISP2 |
23.5% Decrease DNA Methylation |
|
DAA2446 |
protein kinase C binding protein 1 isoform a increases with age |
Molecular |
mesenchymal stem cell |
Human |
ZMYND8 |
19.9% Increase DNA Methylation |
|
DAA2435 |
zinc finger protein 549 increases with age |
Molecular |
mesenchymal stem cell |
Human |
ZNF549 |
19.3% Increase DNA Methylation |
|
DAA676 |
Proliferation rate of mesenchymal stem cells is reduced |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA932 |
Renewal capacity declines |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA2013 |
Number and differentiation potential of adipose tissue-derived stem cells declines with age |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA675 |
Beta-galactosidase expression increases in mesenchymal stem cells |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA678 |
Capacity of mesenchymal stem cells to differentiate into osteoblasts may be decreased |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA673 |
telomere length in hematopoietic stem cells |
Molecular |
hematopoietic stem cells |
Human |
— |
— |
|
DAA2035 |
Alterations in frequency, developmental potential and gene expression profile in hematopoietic stem cells |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA2027 |
DNA damage acummulates in hematopoietic stem and progenitor cells |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA936 |
Volume of hematopoietic bone marrow decreases |
Physiological |
bone marrow |
Human |
— |
— |
|
DAA1073 |
Fewer cells and higher apoptosis |
Physiological |
bone marrow |
Human |
— |
— |
|
DAA1991 |
Hematopoietic cells accumulate random mutations |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|