| DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
| DAA961 |
Increased apoptosis associated with Fas and Fas-ligand expression |
Physiological |
T cell |
Human |
FAS |
— |
|
| DAA1988 |
Decrease in the 24-hour integrated concentration of GH |
Physiological |
plasma |
Human |
GH1 |
— |
|
| DAA1213 |
Circadian GH change |
Physiological |
plasma |
Human |
GH1 |
— |
|
| DAA1181 |
Morning IGF1 decline |
Physiological |
plasma |
Human |
IGF1 |
51.0% Decrease Hormone Level |
|
| DAA962 |
Interleukin-2 production in response to influenza vaccine declines |
Physiological |
T cell |
Human |
IL2 |
— |
|
| DAA1209 |
Blood IL6 level increase |
Physiological |
plasma |
Human |
IL6 |
— |
|
| DAA955 |
Interleukin-7 production declines |
Physiological |
stromal cell |
Human |
IL7 |
— |
|
| DAA1207 |
IL8 level increase |
Physiological |
plasma |
Human |
IL8 |
— |
|
| DAA1199 |
Serum klotho |
Physiological |
plasma |
Human |
KL |
Increase Hormone Level |
|
| DAA2014 |
Microsatellite instability in hematopoietic stem cells and progenitor cells |
Physiological |
hematopoietic stem cells |
Human |
MLH1 |
— |
|
| DAA1215 |
Higher adrenocroticotropic hormone levels |
Physiological |
plasma |
Human |
POMC |
— |
|
| DAA1214 |
Circadian prolactin flattened |
Physiological |
plasma |
Human |
PRL |
— |
|
| DAA2001 |
SIRT1 activity negatively correlated with age in males |
Physiological |
skin |
Human |
SIRT1 |
— |
|
| DAA919 |
Somatostatin basal levels increase |
Physiological |
plasma |
Human |
SST |
— |
|
| DAA1208 |
Blood TNF-alpha level increase |
Physiological |
plasma |
Human |
TNF |
— |
|
| DAA677 |
Proportion of apoptotic cells may be increased |
Physiological |
mesenchymal stem cell |
Human |
TP53 |
— |
|
| DAA1975 |
Loss of subcutaneous adipose skin layer |
Physiological |
skin |
Mouse |
— |
— |
|
| DAA943 |
Lower affinity antibodies generated |
Physiological |
B cell |
Mouse |
— |
— |
|
| DAA1952 |
Possible blunting of growth hormone secretion increase in response to multiple stimuli |
Physiological |
endocrine system |
Mouse |
— |
— |
|
| DAA1943 |
Motor coordination decreases |
Physiological |
musculoskeletal system, nervous system |
Mouse |
— |
— |
|
| DAA1950 |
D-glucose absorption decreased |
Physiological |
endocrine system |
Mouse |
— |
— |
|
| DAA1943 |
Motor coordination decreases |
Physiological |
musculoskeletal system, nervous system |
Mouse |
— |
— |
|
| DAA700 |
Shift in reduced:oxidized glutathione ratio in favour of oxidized gluthione |
Physiological |
blood, lymphocytes |
Mouse |
— |
— |
|
| DAA1947 |
Vitamin C levels decrease |
Physiological |
blood, T cell |
Mouse |
— |
— |
|