| DAA1001 |
Atrophy of hypodermal layer |
Physiological |
subcutaneous |
Human |
— |
— |
|
| DAA999 |
Microvascular alterations in arterioles, capillaries, and venules in dermis/hypodermis |
Physiological |
dermis, subcutaneous |
Human |
— |
— |
|
| DAA2053 |
Sweating capacity decreases |
Physiological |
sweat gland |
Human |
— |
— |
|
| DAA2587 |
Hair greying |
Physiological |
hair |
Human |
— |
— |
|
| DAA2589 |
Male baldness |
Physiological |
hair |
Human |
— |
— |
|
| DAA2588 |
Depletion of hair follicle melanocytes |
Physiological |
hair follicle |
Human |
— |
— |
|
| DAA2413 |
Arylsulfatase G increases with age |
Molecular |
dermis |
Human |
ARSG |
19.6% Increase DNA Methylation |
|
| DAA992 |
Decrease in dermal papillae density |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA2388 |
dehydrogenase/reductase (SDR family) member 3 decreases with age |
Molecular |
dermis |
Human |
DHRS3 |
15.8% Decrease DNA Methylation |
|
| DAA2412 |
calcyphosine isoform b decreases with age |
Molecular |
dermis |
Human |
CAPS |
28.0% Decrease DNA Methylation |
|
| DAA2428 |
aldo-keto reductase family 1; member C3 decreases with age |
Molecular |
dermis |
Human |
AKR1C3 |
19.3% Decrease DNA Methylation |
|
| DAA1004 |
Decreased/disorganized fibril network of dermis |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2406 |
CD34 antigen isoform b decreases with age |
Molecular |
dermis |
Human |
CD34 |
16.6% Decrease DNA Methylation |
|
| DAA995 |
Change in weave of dermis collagen fibers |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2395 |
AMP-activated protein kinase; non-catalytic gamma-3 subunit decreases with age |
Molecular |
dermis |
Human |
PRKAG3 |
20.1% Decrease DNA Methylation |
|
| DAA2431 |
aldehyde dehydrogenase 1A1 decreases with age |
Molecular |
dermis |
Human |
ALDH1A1 |
30.3% Decrease DNA Methylation |
|
| DAA2405 |
chemokine (C-C motif) receptor 1 decreases with age |
Molecular |
dermis |
Human |
CCR1 |
16.5% Decrease DNA Methylation |
|
| DAA996 |
Changes to dermis collagen fiber bundles |
Physiological |
dermis |
Human |
— |
— |
|
| DAA2390 |
chromosome 14 open reading frame 177 decreases with age |
Molecular |
dermis |
Human |
C14orf177 |
16.2% Decrease DNA Methylation |
|
| DAA2392 |
complement factor D preproprotein decreases with age |
Molecular |
dermis |
Human |
CFD |
21.7% Decrease DNA Methylation |
|
| DAA2424 |
C-type lectin domain family 3; member B decreases with age |
Molecular |
dermis |
Human |
CLEC3B |
18.0% Decrease DNA Methylation |
|
| DAA2423 |
cyclin-dependent kinase 5; regulatory subunit 1 decreases with age |
Molecular |
dermis |
Human |
CDK5R1 |
17.2% Decrease DNA Methylation |
|
| DAA2384 |
cyclin-dependent kinase inhibitor 2B isoform 2 increases with age |
Molecular |
dermis |
Human |
CDKN2B |
26.0% Increase DNA Methylation |
|
| DAA1011 |
Changes in glycosaminoglycan/proteoglycan |
Physiological |
epidermis, dermis |
Human |
— |
— |
|
| DAA2393 |
ATP-binding cassette; sub-family A member 8 decreases with age |
Molecular |
dermis |
Human |
ABCA8 |
23.4% Decrease DNA Methylation |
|