DAA1076 |
Progressive liquefaction |
Physiological |
vitreous humor |
Human |
— |
— |
|
DAA1075 |
Presbycusis |
Pathological |
cochlea |
Human |
— |
— |
|
DAA1945 |
Memory consolidation is impaired |
Psychological |
brain |
Mouse |
— |
— |
|
DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA1943 |
Motor coordination decreases |
Physiological |
musculoskeletal system, nervous system |
Mouse |
— |
— |
|
DAA737 |
Permeability increases with age |
Physiological |
blood brain barrier |
Human |
— |
— |
|
DAA2036 |
Neural stem cell pool declines |
Physiological |
hippocampus |
Mouse |
— |
— |
|
DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|
DAA757 |
Parkinsonian signs |
Physiological |
nervous system |
Human |
— |
— |
|
DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
DAA714 |
Neuronal soma shrinks in size |
Physiological |
brain |
Human |
— |
— |
|
DAA1938 |
No clear changes in anxiety but decrease in ambulation |
Psychological |
brain |
Mouse |
— |
— |
|
DAA721 |
Neurofibrillary tangles and Lewy bodies in neurons |
Physiological |
brain |
Human |
— |
— |
|
DAA2026 |
Mutations in mitochondrial DNA accumulate |
Physiological |
heart, kidney, skeletal muscle, cerebral cortex, cerebellum |
Human |
— |
— |
|
DAA2026 |
Mutations in mitochondrial DNA accumulate |
Physiological |
heart, kidney, skeletal muscle, cerebral cortex, cerebellum |
Human |
— |
— |
|
DAA1224 |
MTHFR methylation decrease |
Molecular |
prefrontal cortex |
Human |
— |
— |
|
DAA742 |
Motor function impairment evident in altered gait and balance |
Physiological |
nervous system |
Human |
— |
— |
|