DAA1217 |
Brain volume decrease |
Physiological |
brain |
Human |
— |
— |
|
DAA1993 |
Brain volume decreases in a regional-specific way |
Physiological |
brain |
Human |
— |
— |
|
DAA765 |
Calcium binding capacity decreases in neurons |
Physiological |
brain |
Human |
— |
— |
|
DAA732 |
Glial cell number |
Physiological |
cerebral cortex |
Human |
— |
— |
|
DAA2028 |
Eye lenses become much stiffer |
Physiological |
lens |
Human |
— |
— |
|
DAA724 |
Global neuron loss |
Physiological |
cerebral cortex |
Human |
— |
— |
|
DAA714 |
Neuronal soma shrinks in size |
Physiological |
brain |
Human |
— |
— |
|
DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|
DAA1076 |
Progressive liquefaction |
Physiological |
vitreous humor |
Human |
— |
— |
|
DAA763 |
Prolongation of calcium signals in nerve cells |
Physiological |
brain |
Human |
— |
— |
|
DAA729 |
Gray matter volume decreases |
Physiological |
grey matter |
Human |
— |
— |
|
DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
DAA2032 |
The ratio of free to bound water increases |
Physiological |
lens |
Human |
— |
— |
|
DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
Physiological |
brain |
Human |
— |
— |
|
DAA1981 |
Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra |
Physiological |
substantia nigra |
Human |
— |
— |
|
DAA718 |
Synaptic density slightly decreases at advanced ages |
Physiological |
frontal lobe |
Human |
— |
— |
|
DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
Physiological |
brain |
Human |
— |
— |
|
DAA786 |
Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
DAA752 |
Earlier sleep and wake time |
Psychological |
brain |
Human |
— |
— |
|
DAA776 |
Verbal memory declines |
Psychological |
brain |
Human |
— |
— |
|
DAA1945 |
Memory consolidation is impaired |
Psychological |
brain |
Mouse |
— |
— |
|
DAA777 |
Visual memory declines |
Psychological |
brain |
Human |
— |
— |
|
DAA753 |
Cognitive deficits |
Psychological |
brain |
Human |
— |
— |
|