| DAA727 |
Axon loss |
Physiological |
white matter |
Human |
— |
— |
|
| DAA728 |
Brain matter volume declines |
Physiological |
brain |
Human |
— |
— |
|
| DAA729 |
Gray matter volume decreases |
Physiological |
grey matter |
Human |
— |
— |
|
| DAA730 |
White matter volume decreases |
Physiological |
white matter |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA732 |
Glial cell number |
Physiological |
cerebral cortex |
Human |
— |
— |
|
| DAA733 |
Neurotransmitter and neuro receptor concentrations are altered |
Physiological |
brain |
Human |
— |
— |
|
| DAA735 |
Localized increases and decreases in synaptic transmission |
Physiological |
brain |
Human |
— |
— |
|
| DAA737 |
Permeability increases with age |
Physiological |
blood brain barrier |
Human |
— |
— |
|
| DAA738 |
Cerebral spinal fluid amount increases |
Physiological |
brain |
Human |
— |
— |
|
| DAA739 |
Degeneration of dopamine neurons and receptors |
Physiological |
brain |
Human |
— |
— |
|
| DAA740 |
Cortical plasticity decreases |
Physiological |
brain |
Human |
— |
— |
|
| DAA741 |
Cerebral blood flow and glucose utilization are reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA743 |
Sensitivity of HPA axis is impaired |
Physiological |
pituitary gland, adrenal gland, hypothalamus |
Human |
— |
— |
|
| DAA744 |
EEG alterations during auditory test |
Physiological |
brain |
Human |
— |
— |
|
| DAA762 |
Down regulation of calcium clearance from nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA763 |
Prolongation of calcium signals in nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA764 |
Depolarization of mitochondria |
Physiological |
brain |
Human |
— |
— |
|
| DAA765 |
Calcium binding capacity decreases in neurons |
Physiological |
brain |
Human |
— |
— |
|
| DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA780 |
Medial temporal activation during encoding and retrieval of memory is reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA783 |
Increased sustained activity in tests of working memory |
Physiological |
brain |
Human |
— |
— |
|
| DAA784 |
Increased transient activity in non-spatial auditory working memory test |
Physiological |
brain |
Human |
— |
— |
|
| DAA785 |
Reduced hippocampal activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|