DAA952 |
Fewer CD4+ and CD8+ cells |
Physiological |
T cell |
Human |
— |
— |
|
DAA963 |
Expansion into effector cells is reduced |
Physiological |
naïve T cell |
Human |
— |
— |
|
DAA965 |
Incidence of anergia increases |
Physiological |
immune system |
Human |
— |
— |
|
DAA1230 |
E-rosette-forming cells decrease |
Physiological |
thymus |
Human |
— |
— |
|
DAA983 |
Diminished superoxide production in response to Fc |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA1229 |
Declining T-lymphocyte production in the thymus |
Physiological |
thymus |
Human |
— |
— |
|
DAA986 |
Cytotoxicity and interleukin-2 response of natural killer cells decreases |
Physiological |
natural killer cell |
Human |
— |
— |
|
DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA973 |
Chemotaxis and respiratory burst capacity in response to GM-CSF priming decreased |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA972 |
Chemotaxis and adhesion activity unchanged in vitro |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA940 |
B naive cells' susceptibility to apoptosis decreases |
Physiological |
memory B cell |
Human |
— |
— |
|
DAA1947 |
Vitamin C levels decrease |
Physiological |
blood, T cell |
Mouse |
— |
— |
|
DAA979 |
Apoptotic pathway in response to stimuli disrupted |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA700 |
Shift in reduced:oxidized glutathione ratio in favour of oxidized gluthione |
Physiological |
blood, lymphocytes |
Mouse |
— |
— |
|
DAA943 |
Lower affinity antibodies generated |
Physiological |
B cell |
Mouse |
— |
— |
|