All changes for the tissue immune system (42)

Identifier Name Type Tissues Organism Gene Data Actions
DAA1229 Declining T-lymphocyte production in the thymus Physiological thymus Human
DAA1230 E-rosette-forming cells decrease Physiological thymus Human
DAA1947 Vitamin C levels decrease Physiological blood, T cell Mouse
DAA1953 Interleukin-6 plasma levels are elevated in response to acute systemic inflammation Physiological immune system Mouse
DAA2599 Telomere shortening Physiological adipose tissue, skeletal muscle, skin, leukocyte Human
DAA700 Shift in reduced:oxidized glutathione ratio in favour of oxidized gluthione Physiological blood, lymphocytes Mouse
DAA934 Number of mature B cells leaving the bone marrow declines Physiological bone marrow, B cell Human
DAA935 Pro-B cell generation and differentiation declines Physiological bone marrow, B cell Human
DAA939 Naive cell number increases and memory cells decrease Physiological B cell Human
DAA940 B naive cells' susceptibility to apoptosis decreases Physiological memory B cell Human
DAA943 Lower affinity antibodies generated Physiological B cell Mouse
DAA944 Less antibodies generated Physiological B cell Human
DAA945 Thymus involution Physiological thymus Human
DAA948 Volume of perivascular space around thymus increases Physiological thymus Human
DAA950 Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals Physiological immune system Human
DAA952 Fewer CD4+ and CD8+ cells Physiological T cell Human
DAA953 Increase in cells that are both CD8+ and CD28-null Physiological T regulatory cell Human
DAA954 Number of T cell progenitors declines Physiological T cell progenitor Human
DAA955 Interleukin-7 production declines Physiological stromal cell Human IL7
DAA956 Proliferation is reduced Physiological lymphocytes Human
DAA961 Increased apoptosis associated with Fas and Fas-ligand expression Physiological T cell Human FAS
DAA962 Interleukin-2 production in response to influenza vaccine declines Physiological T cell Human IL2
DAA963 Expansion into effector cells is reduced Physiological naïve T cell Human
DAA964 T-cell diversity declines Physiological T cell Human
DAA965 Incidence of anergia increases Physiological immune system Human