All physiological changes (343)

Identifier Name Data Tissues Organism Actions
DAA726 Demyelination — white matter Human
DAA727 Axon loss — white matter Human
DAA725 Leukoaraiosis — white matter Human
DAA731 Mean diffusivity increases and water diffusion anisotropy decreases — corpus callosum, white matter Human
DAA730 White matter volume decreases — white matter Human
DAA731 Mean diffusivity increases and water diffusion anisotropy decreases — corpus callosum, white matter Human
DAA2026 Mutations in mitochondrial DNA accumulate — heart, kidney, skeletal muscle, cerebral cortex, cerebellum Human
DAA1981 Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra — substantia nigra Human
DAA722 Accumulation of neuromelanin in dopaminergic nigral neurons — substantia nigra Human
DAA743 Sensitivity of HPA axis is impaired — pituitary gland, adrenal gland, hypothalamus Human
DAA1984 Layer-specific dendritic regression of pyramidal cells — prefrontal cortex Human
DAA718 Synaptic density slightly decreases at advanced ages — frontal lobe Human
DAA2026 Mutations in mitochondrial DNA accumulate — heart, kidney, skeletal muscle, cerebral cortex, cerebellum Human
DAA732 Glial cell number — cerebral cortex Human
DAA724 Global neuron loss — cerebral cortex Human
DAA786 Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity — brain Human
DAA783 Increased sustained activity in tests of working memory — brain Human
DAA764 Depolarization of mitochondria — brain Human
DAA765 Calcium binding capacity decreases in neurons — brain Human
DAA717 Dendrite regression, reduction in dendrite length — brain Human
DAA723 Accumulation of extracellular neuritic plaques — brain Human
DAA1993 Brain volume decreases in a regional-specific way — brain Human
DAA1217 Brain volume decrease — brain Human
DAA728 Brain matter volume declines — brain Human
DAA2041 Altered brain mitochondrial metabolism — brain Human