All physiological changes (343)

Identifier Name Data Tissues Organism Actions
DAA2596 Frequency of mitochondrial DNA deletions increases with age — brain Human
DAA763 Prolongation of calcium signals in nerve cells — brain Human
DAA1980 Reaction time for a visually paced simple motor task increases with age — brain Human
DAA785 Reduced hippocampal activity and functional connectivity in tests for verbal familiarity — brain Human
DAA744 EEG alterations during auditory test — brain Human
DAA762 Down regulation of calcium clearance from nerve cells — brain Human
DAA764 Depolarization of mitochondria — brain Human
DAA739 Degeneration of dopamine neurons and receptors — brain Human
DAA740 Cortical plasticity decreases — brain Human
DAA723 Accumulation of extracellular neuritic plaques — brain Human
DAA738 Cerebral spinal fluid amount increases — brain Human
DAA741 Cerebral blood flow and glucose utilization are reduced — brain Human
DAA765 Calcium binding capacity decreases in neurons — brain Human
DAA1993 Brain volume decreases in a regional-specific way — brain Human
DAA1217 Brain volume decrease — brain Human
DAA728 Brain matter volume declines — brain Human
DAA1996 Beta-amyloid protein deposition increases — brain Human
DAA788 Viscoelastic modulus of brain tissue decreases — brain Human
DAA2041 Altered brain mitochondrial metabolism — brain Human
DAA2026 Mutations in mitochondrial DNA accumulate — heart, kidney, skeletal muscle, cerebral cortex, cerebellum Human
DAA732 Glial cell number — cerebral cortex Human
DAA724 Global neuron loss — cerebral cortex Human
DAA718 Synaptic density slightly decreases at advanced ages — frontal lobe Human
DAA1984 Layer-specific dendritic regression of pyramidal cells — prefrontal cortex Human
DAA743 Sensitivity of HPA axis is impaired — pituitary gland, adrenal gland, hypothalamus Human