Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2135 major histocompatibility complex, class II, DR beta 1 increases with age Molecular hippocampus Human HLA-DRB1 193.5% Increase Gene Expression Level
DAA2136 major histocompatibility complex, class II, DR beta 1 increases with age Molecular parietal lobe Human HLA-DRB1 90.3% Increase Gene Expression Level
DAA2137 major histocompatibility complex, class II, DR beta 1 increases with age Molecular frontal lobe Human HLA-DRB1 83.0% Increase Gene Expression Level
DAA2138 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular temporal lobe Human FCGR1A 151.0% Increase Gene Expression Level
DAA2139 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular temporal lobe Human FCGR1B 166.0% Increase Gene Expression Level
DAA2140 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular hippocampus Human FCGR1A 423.1% Increase Gene Expression Level
DAA2141 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular hippocampus Human FCGR1B 434.2% Increase Gene Expression Level
DAA2142 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular parietal lobe Human FCGR1A 207.6% Increase Gene Expression Level
DAA2143 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular parietal lobe Human FCGR1B 225.5% Increase Gene Expression Level
DAA2144 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular frontal lobe Human FCGR1A 157.3% Increase Gene Expression Level
DAA2145 Fc fragment of IgG, high affinity Ib, receptor (CD64) increases with age Molecular frontal lobe Human FCGR1B 170.4% Increase Gene Expression Level
DAA2146 complement component 4A increases with age Molecular temporal lobe Human C4A 115.3% Increase Gene Expression Level
DAA2147 complement component 4B increases with age Molecular temporal lobe Human C4B 289.9% Increase Gene Expression Level
DAA2148 complement component 4A increases with age Molecular hippocampus Human C4A 226.3% Increase Gene Expression Level
DAA2149 complement component 4A increases with age Molecular hippocampus Human C4A 216.4% Increase Gene Expression Level
DAA2150 complement component 4B increases with age Molecular hippocampus Human C4B 466.1% Increase Gene Expression Level
DAA2151 complement component 4A increases with age Molecular parietal lobe Human C4A 153.8% Increase Gene Expression Level
DAA2152 complement component 4B increases with age Molecular parietal lobe Human C4B 444.8% Increase Gene Expression Level
DAA2153 complement component 4A increases with age Molecular frontal lobe Human C4A 187.3% Increase Gene Expression Level
DAA2154 complement component 4B increases with age Molecular frontal lobe Human C4B 895.9% Increase Gene Expression Level
DAA2155 Major histocompatibility complex, class II, DQ alpha 1 increases with age Molecular hippocampus Human HLA-DQA1 496.7% Increase Gene Expression Level
DAA2156 Major histocompatibility complex, class II, DQ alpha 1 increases with age Molecular parietal lobe Human HLA-DQA1 203.7% Increase Gene Expression Level
DAA2157 complement factor H-related 1 increases with age Molecular hippocampus Human CFHR1 88.0% Increase Gene Expression Level
DAA2158 complement factor H-related 1 increases with age Molecular parietal lobe Human CFHR1 126.5% Increase Gene Expression Level
DAA2159 complement factor H-related 1 increases with age Molecular frontal lobe Human CFHR1 144.2% Increase Gene Expression Level