protein kinase C, zeta

Symbol

PRKCZ (may also be known as: PKC2)

Organism

Human

Orthologs

SymbolSpecies
pkc-3 Caenorhabditis elegans
aPKC Drosophila melanogaster
prkcz Danio rerio
Prkcz Mus musculus
Prkcz Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA188 protein kinase C, zeta Molecular brain Human PRKCZ 12.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000226 microtubule cytoskeleton organization biological_process
GO:0006468 protein phosphorylation biological_process
GO:0006916 anti-apoptosis biological_process
GO:0006954 inflammatory response biological_process
GO:0007165 signal transduction biological_process
GO:0007596 blood coagulation biological_process
GO:0018105 peptidyl-serine phosphorylation biological_process
GO:0030010 establishment of cell polarity biological_process
GO:0030168 platelet activation biological_process
GO:0031333 negative regulation of protein complex assembly biological_process
GO:0032753 positive regulation of interleukin-4 production biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0045630 positive regulation of T-helper 2 cell differentiation biological_process
GO:0046627 negative regulation of insulin receptor signaling pathway biological_process
GO:0046628 positive regulation of insulin receptor signaling pathway biological_process
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0051092 positive regulation of NF-kappaB transcription factor activity biological_process
GO:0060291 long-term synaptic potentiation biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:2000463 positive regulation of excitatory postsynaptic membrane potential biological_process
GO:2000553 positive regulation of T-helper 2 cell cytokine production biological_process
GO:2000664 positive regulation of interleukin-5 secretion biological_process
GO:2000667 positive regulation of interleukin-13 secretion biological_process
GO:2001181 positive regulation of interleukin-10 secretion biological_process
GO:0005624 membrane fraction cellular_component
GO:0005625 soluble fraction cellular_component
GO:0005634 nucleus cellular_component
GO:0005635 nuclear envelope cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005768 endosome cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005911 cell-cell junction cellular_component
GO:0005923 tight junction cellular_component
GO:0005938 cell cortex cellular_component
GO:0016363 nuclear matrix cellular_component
GO:0035748 myelin sheath abaxonal region cellular_component
GO:0043234 protein complex cellular_component
GO:0045179 apical cortex cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004697 protein kinase C activity molecular_function
GO:0005515 protein binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0016772 transferase activity, transferring phosphorus-containing groups molecular_function
GO:0043560 insulin receptor substrate binding molecular_function
GO:0046872 metal ion binding molecular_function