protein kinase, cGMP-dependent, type II

Symbol

PRKG2 (may also be known as: None)

Organism

Human

Description

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Orthologs

SymbolSpecies
prkg2 Danio rerio
Prkg2 Mus musculus
Prkg2 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006468 protein phosphorylation biological_process
GO:0007165 signal transduction biological_process
GO:0007596 blood coagulation biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0046209 nitric oxide metabolic process biological_process
GO:0050999 regulation of nitric-oxide synthase activity biological_process
GO:0005829 cytosol cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0004672 protein kinase activity molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004692 cGMP-dependent protein kinase activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0030553 cGMP binding molecular_function