DAA982 |
expression of CD16 receptor diminished |
Molecular |
neutrophil |
Human |
FCGR3A |
— |
|
DAA981 |
Phagocytosis activity unchanged in response to unopsonized targets |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA980 |
Phagocytosis activity decreased in response to opsonized targets |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA98 |
glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
Molecular |
brain |
Human |
GRIN2A |
18.0% Decrease Gene Expression Level |
|
DAA979 |
Apoptotic pathway in response to stimuli disrupted |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA977 |
ROS production in response to stimuli unchanged |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA975 |
Infiltration at injury site is reduced |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA974 |
Chemotaxis is reduced |
Physiological |
neutrophil, dendritic cell |
Human |
— |
— |
|
DAA973 |
Chemotaxis and respiratory burst capacity in response to GM-CSF priming decreased |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA972 |
Chemotaxis and adhesion activity unchanged in vitro |
Physiological |
neutrophil |
Human |
— |
— |
|
DAA97 |
glutamate receptor, ionotropic, AMPA 1 |
Molecular |
brain |
Human |
GRIA1 |
17.0% Decrease Gene Expression Level |
|
DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
DAA968 |
Chronic inflammation increases |
Physiological |
blood, immune system |
Human |
— |
— |
|
DAA966 |
Vaccination antibody response is impaired |
Physiological |
immune system |
Human |
— |
— |
|
DAA965 |
Incidence of anergia increases |
Physiological |
immune system |
Human |
— |
— |
|
DAA964 |
T-cell diversity declines |
Physiological |
T cell |
Human |
— |
— |
|
DAA963 |
Expansion into effector cells is reduced |
Physiological |
naïve T cell |
Human |
— |
— |
|
DAA962 |
Interleukin-2 production in response to influenza vaccine declines |
Physiological |
T cell |
Human |
IL2 |
— |
|
DAA961 |
Increased apoptosis associated with Fas and Fas-ligand expression |
Physiological |
T cell |
Human |
FAS |
— |
|
DAA960 |
Receptor expression alterations |
Physiological |
grey matter |
Human |
— |
— |
|
DAA96 |
G protein-coupled receptor, family C, group 5, member B |
Molecular |
brain |
Human |
GPRC5B |
10.0% Increase Gene Expression Level |
|
DAA959 |
telomere shortening |
Molecular |
naïve T cell |
Human |
— |
— |
|
DAA956 |
Proliferation is reduced |
Physiological |
lymphocytes |
Human |
— |
— |
|
DAA955 |
Interleukin-7 production declines |
Physiological |
stromal cell |
Human |
IL7 |
— |
|