DAA1952 |
Possible blunting of growth hormone secretion increase in response to multiple stimuli |
Physiological |
endocrine system |
Mouse |
— |
— |
|
DAA1953 |
Interleukin-6 plasma levels are elevated in response to acute systemic inflammation |
Physiological |
immune system |
Mouse |
— |
— |
|
DAA1954 |
Interleukin-15 levels decrease in plasma and muscle |
Physiological |
plasma, muscle |
Mouse |
— |
— |
|
DAA1954 |
Interleukin-15 levels decrease in plasma and muscle |
Physiological |
plasma, muscle |
Mouse |
— |
— |
|
DAA1959 |
Osteoblast differentiation decreases |
Physiological |
bone marrow |
Mouse |
— |
— |
|
DAA1960 |
Adipocyte formation increases |
Physiological |
bone marrow |
Mouse |
— |
— |
|
DAA1971 |
Pancreatic Beta-cell replication decrease |
Physiological |
pancreas |
Mouse |
— |
— |
|
DAA1974 |
Bone loss |
Physiological |
bone |
Mouse |
— |
— |
|
DAA1975 |
Loss of subcutaneous adipose skin layer |
Physiological |
skin |
Mouse |
— |
— |
|
DAA1978 |
Age differences in classical conditioning of the eyelid response |
Physiological |
eyelid |
Human |
— |
— |
|
DAA1980 |
Reaction time for a visually paced simple motor task increases with age |
Physiological |
brain |
Human |
— |
— |
|
DAA1981 |
Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra |
Physiological |
substantia nigra |
Human |
— |
— |
|
DAA1983 |
Critical decline in fine motor hand movements |
Physiological |
nervous system |
Human |
— |
— |
|
DAA1984 |
Layer-specific dendritic regression of pyramidal cells |
Physiological |
prefrontal cortex |
Human |
— |
— |
|
DAA1985 |
Diastolic dysfunction with aging |
Physiological |
cardiovascular system |
Human |
— |
— |
|
DAA1988 |
Decrease in the 24-hour integrated concentration of GH |
Physiological |
plasma |
Human |
GH1 |
— |
|
DAA1990 |
Number of mutations in offsprings increases |
Physiological |
male reproductive system |
Human |
— |
— |
|
DAA1991 |
Hematopoietic cells accumulate random mutations |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA1992 |
Muscle mass and strength loss |
Physiological |
skeletal muscle |
Human |
— |
— |
|
DAA1993 |
Brain volume decreases in a regional-specific way |
Physiological |
brain |
Human |
— |
— |
|
DAA1994 |
Increase in collagen in the arterial intima |
Physiological |
arterial intima |
Human |
— |
100.0% Increase Protein level |
|
DAA1995 |
Decrease in collagen in the venous intima |
Physiological |
venous intima |
Human |
— |
42.0% Decrease Protein level |
|
DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
DAA2001 |
SIRT1 activity negatively correlated with age in males |
Physiological |
skin |
Human |
SIRT1 |
— |
|
DAA2013 |
Number and differentiation potential of adipose tissue-derived stem cells declines with age |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|