DAA702 |
Ratio of oxidized to unoxidized plasma albumin increases |
Physiological |
plasma |
Human |
— |
— |
|
DAA676 |
Proliferation rate of mesenchymal stem cells is reduced |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA920 |
Prolactin increases in males |
Physiological |
plasma |
Human |
— |
— |
|
DAA2022 |
Prolactin decreases in females |
Physiological |
plasma |
Human |
— |
— |
|
DAA935 |
Pro-B cell generation and differentiation declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA917 |
Plasma and urinary catecholamine elevation after stimuli |
Physiological |
plasma |
Human |
— |
— |
|
DAA701 |
Oxidative increase in cystine/cysteine ratio |
Physiological |
plasma |
Human |
— |
— |
|
DAA934 |
Number of mature B cells leaving the bone marrow declines |
Physiological |
bone marrow, B cell |
Human |
— |
— |
|
DAA2013 |
Number and differentiation potential of adipose tissue-derived stem cells declines with age |
Physiological |
mesenchymal stem cell |
Human |
— |
— |
|
DAA933 |
No changes in erythroid and myeloid progenitor cells evident |
Physiological |
myeloid progenitor cell |
Human |
— |
— |
|
DAA2058 |
Mosaic abnormalities increase |
Physiological |
blood, oral cavity |
Human |
— |
— |
|
DAA1218 |
Morning concentrations of oestradiol decline |
Physiological |
plasma |
Human |
— |
— |
|
DAA1221 |
Morning concentration of sex-hormone binding globulin declines |
Physiological |
plasma |
Human |
— |
— |
|
DAA1219 |
Morning concentration of oestrone (E1) declines |
Physiological |
plasma |
Human |
— |
— |
|
DAA2597 |
Mitochondrial DNA content in non-centenerians decreases with age |
Physiological |
blood |
Human |
— |
— |
|
DAA909 |
Mean blood glucose level increases |
Physiological |
plasma |
Human |
— |
— |
|
DAA925 |
Increase in follicle stimulating hormone (FSH) and luteinizing hormone (LH) preceding menopause |
Physiological |
plasma |
Human |
— |
— |
|
DAA2593 |
Glycosylation of immunoglobulin G molecules changes with age |
Physiological |
blood |
Human |
— |
— |
|
DAA1991 |
Hematopoietic cells accumulate random mutations |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA1073 |
Fewer cells and higher apoptosis |
Physiological |
bone marrow |
Human |
— |
— |
|
DAA2027 |
DNA damage acummulates in hematopoietic stem and progenitor cells |
Physiological |
hematopoietic stem cells |
Human |
— |
— |
|
DAA910 |
DHEA levels decrease |
Physiological |
plasma |
Human |
— |
— |
|
DAA921 |
Decrease in melatonin concentration and loss of circadian rhythm for secretion |
Physiological |
plasma, pineal gland |
Human |
— |
— |
|
DAA916 |
Cortisol levels increased |
Physiological |
plasma |
Human |
— |
— |
|
DAA677 |
Proportion of apoptotic cells may be increased |
Physiological |
mesenchymal stem cell |
Human |
TP53 |
— |
|