| DAA1076 |
Progressive liquefaction |
Physiological |
vitreous humor |
Human |
— |
— |
|
| DAA1217 |
Brain volume decrease |
Physiological |
brain |
Human |
— |
— |
|
| DAA1941 |
Gait width increases |
Physiological |
nervous system |
Mouse |
— |
— |
|
| DAA1943 |
Motor coordination decreases |
Physiological |
musculoskeletal system, nervous system |
Mouse |
— |
— |
|
| DAA1948 |
Neurogenesis is reduced |
Physiological |
brain |
Mouse |
— |
— |
|
| DAA1949 |
Intracellular glutathione content decreases |
Physiological |
brain |
Mouse |
— |
— |
|
| DAA1978 |
Age differences in classical conditioning of the eyelid response |
Physiological |
eyelid |
Human |
— |
— |
|
| DAA1980 |
Reaction time for a visually paced simple motor task increases with age |
Physiological |
brain |
Human |
— |
— |
|
| DAA1981 |
Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra |
Physiological |
substantia nigra |
Human |
— |
— |
|
| DAA1983 |
Critical decline in fine motor hand movements |
Physiological |
nervous system |
Human |
— |
— |
|
| DAA1984 |
Layer-specific dendritic regression of pyramidal cells |
Physiological |
prefrontal cortex |
Human |
— |
— |
|
| DAA1993 |
Brain volume decreases in a regional-specific way |
Physiological |
brain |
Human |
— |
— |
|
| DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
| DAA2026 |
Mutations in mitochondrial DNA accumulate |
Physiological |
heart, kidney, skeletal muscle, cerebral cortex, cerebellum |
Human |
— |
— |
|
| DAA2026 |
Mutations in mitochondrial DNA accumulate |
Physiological |
heart, kidney, skeletal muscle, cerebral cortex, cerebellum |
Human |
— |
— |
|
| DAA2028 |
Eye lenses become much stiffer |
Physiological |
lens |
Human |
— |
— |
|
| DAA2029 |
Color of lenses increases |
Physiological |
lens |
Human |
— |
— |
|
| DAA2030 |
Transmission of visible light through eye lenses decreases |
Physiological |
lens |
Human |
— |
— |
|
| DAA2031 |
Altered concentration of sodium, potassium and calcium |
Physiological |
lens |
Human |
— |
— |
|
| DAA2032 |
The ratio of free to bound water increases |
Physiological |
lens |
Human |
— |
— |
|
| DAA2033 |
Alterations in structural proteins and cell membranes in the lenses |
Physiological |
lens |
Human |
— |
— |
|
| DAA2036 |
Neural stem cell pool declines |
Physiological |
hippocampus |
Mouse |
— |
— |
|
| DAA2037 |
Decrease in mitochondrial content and oxidative metabolism in cells |
Physiological |
brain |
Mouse |
— |
— |
|
| DAA2041 |
Altered brain mitochondrial metabolism |
Physiological |
brain |
Human |
— |
— |
|
| DAA2583 |
Vision loss |
Physiological |
visual apparatus |
Human |
— |
— |
|