| DAA960 |
Receptor expression alterations |
Physiological |
grey matter |
Human |
— |
— |
|
| DAA743 |
Sensitivity of HPA axis is impaired |
Physiological |
pituitary gland, adrenal gland, hypothalamus |
Human |
— |
— |
|
| DAA785 |
Reduced hippocampal activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
| DAA762 |
Down regulation of calcium clearance from nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA731 |
Mean diffusivity increases and water diffusion anisotropy decreases |
Physiological |
corpus callosum, white matter |
Human |
— |
— |
|
| DAA723 |
Accumulation of extracellular neuritic plaques |
Physiological |
brain |
Human |
— |
— |
|
| DAA2596 |
Frequency of mitochondrial DNA deletions increases with age |
Physiological |
brain |
Human |
— |
— |
|
| DAA2595 |
Frequency of somatic mitochondrial mutations increases with age |
Physiological |
brain |
Human |
— |
— |
|
| DAA787 |
Increased bilateral anterior frontal activity in memory interference tests |
Physiological |
brain |
Human |
— |
— |
|
| DAA786 |
Increased rhinal cortex activity and functional connectivity in tests for verbal familiarity |
Physiological |
brain |
Human |
— |
— |
|
| DAA730 |
White matter volume decreases |
Physiological |
white matter |
Human |
— |
— |
|
| DAA783 |
Increased sustained activity in tests of working memory |
Physiological |
brain |
Human |
— |
— |
|
| DAA784 |
Increased transient activity in non-spatial auditory working memory test |
Physiological |
brain |
Human |
— |
— |
|
| DAA779 |
Prefrontal cortex activation during learning is reduced |
Physiological |
brain |
Human |
— |
— |
|
| DAA718 |
Synaptic density slightly decreases at advanced ages |
Physiological |
frontal lobe |
Human |
— |
— |
|
| DAA763 |
Prolongation of calcium signals in nerve cells |
Physiological |
brain |
Human |
— |
— |
|
| DAA740 |
Cortical plasticity decreases |
Physiological |
brain |
Human |
— |
— |
|
| DAA727 |
Axon loss |
Physiological |
white matter |
Human |
— |
— |
|
| DAA721 |
Neurofibrillary tangles and Lewy bodies in neurons |
Physiological |
brain |
Human |
— |
— |
|
| DAA1996 |
Beta-amyloid protein deposition increases |
Physiological |
brain |
Human |
APP |
— |
|
| DAA714 |
Neuronal soma shrinks in size |
Physiological |
brain |
Human |
— |
— |
|
| DAA728 |
Brain matter volume declines |
Physiological |
brain |
Human |
— |
— |
|
| DAA1217 |
Brain volume decrease |
Physiological |
brain |
Human |
— |
— |
|
| DAA1993 |
Brain volume decreases in a regional-specific way |
Physiological |
brain |
Human |
— |
— |
|