Lu et al. (2004) "Gene regulation and DNA damage in the ageing human brain." Nature 429(6994):883-891 (PubMed) (255 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA167 protein-L-isoaspartate (D-aspartate) O-methyltransferase Molecular brain Human PCMT1 12.0% Decrease Gene Expression Level
DAA168 PCTAIRE protein kinase 2 Molecular brain Human PCTK2 19.0% Decrease Gene Expression Level
DAA169 phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) Molecular brain Human PDE4D 21.0% Decrease Gene Expression Level
DAA17 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle Molecular brain Human ATP5A1 17.0% Decrease Gene Expression Level
DAA170 PDZ and LIM domain 3 Molecular brain Human PDLIM3 22.0% Increase Gene Expression Level
DAA171 FERM and PDZ domain containing 4 Molecular brain Human FRMPD4 22.0% Decrease Gene Expression Level
DAA172 profilin 2 Molecular brain Human PFN2 4.0% Decrease Gene Expression Level
DAA173 protein inhibitor of activated STAT, 2 Molecular brain Human PIAS2 10.0% Decrease Gene Expression Level
DAA174 protein inhibitor of activated STAT, 3 Molecular brain Human PIAS3 10.0% Increase Gene Expression Level
DAA175 phosphatidylinositol glycan anchor biosynthesis, class C Molecular brain Human PIGC 5.0% Decrease Gene Expression Level
DAA176 phosphatidylinositol transfer protein, beta Molecular brain Human PITPNB 17.0% Decrease Gene Expression Level
DAA177 phospholipase C-like 2 Molecular brain Human PLCL2 10.0% Decrease Gene Expression Level
DAA178 phospholipase D family, member 3 Molecular brain Human PLD3 10.0% Decrease Gene Expression Level
DAA179 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 Molecular brain Human PLOD2 24.0% Increase Gene Expression Level
DAA18 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide Molecular brain Human ATP5B 9.0% Decrease Gene Expression Level
DAA180 plexin B1 Molecular brain Human PLXNB1 11.0% Increase Gene Expression Level
DAA181 POU class 6 homeobox 1 Molecular brain Human POU6F1 4.0% Decrease Gene Expression Level
DAA182 protein phosphatase 1E (PP2C domain containing) Molecular brain Human PPM1E 17.0% Decrease Gene Expression Level
DAA183 protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform Molecular brain Human PPP2R1A 6.0% Decrease Gene Expression Level
DAA184 protein phosphatase 5, catalytic subunit Molecular brain Human PPP5C 7.0% Decrease Gene Expression Level
DAA185 peroxiredoxin 6 Molecular brain Human PRDX6 11.0% Increase Gene Expression Level
DAA186 protein kinase C, beta Molecular brain Human PRKCB 11.0% Decrease Gene Expression Level
DAA187 protein kinase C, gamma Molecular brain Human PRKCG 12.0% Decrease Gene Expression Level
DAA188 protein kinase C, zeta Molecular brain Human PRKCZ 12.0% Decrease Gene Expression Level
DAA189 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Molecular brain Human PSMD8 8.0% Decrease Gene Expression Level