Cribbs et al. (2012) "Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study." J Neuroinflammation 9:179 (PubMed) (248 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA2147 complement component 4B increases with age Molecular temporal lobe Human C4B 289.9% Increase Gene Expression Level
DAA2176 complement component 5a receptor 1 increases with age Molecular hippocampus Human C5AR1 166.2% Increase Gene Expression Level
DAA2189 complement component 5a receptor 1 increases with age Molecular parietal lobe Human C5AR1 34.3% Increase Gene Expression Level
DAA2188 complement component 5 increases with age Molecular parietal lobe Human C5 35.3% Increase Gene Expression Level
DAA2199 complement component 5 increases with age Molecular frontal lobe Human C5 43.7% Increase Gene Expression Level
DAA2200 complement factor H increases with age Molecular frontal lobe Human CFH 210.8% Increase Gene Expression Level
DAA2190 complement factor H increases with age Molecular parietal lobe Human CFH 138.9% Increase Gene Expression Level
DAA2177 complement factor H increases with age Molecular hippocampus Human CFH 166.8% Increase Gene Expression Level
DAA2158 complement factor H-related 1 increases with age Molecular parietal lobe Human CFHR1 126.5% Increase Gene Expression Level
DAA2157 complement factor H-related 1 increases with age Molecular hippocampus Human CFHR1 88.0% Increase Gene Expression Level
DAA2159 complement factor H-related 1 increases with age Molecular frontal lobe Human CFHR1 144.2% Increase Gene Expression Level
DAA2269 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular temporal lobe Human FCER1G 144.2% Increase Gene Expression Level
DAA2281 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular parietal lobe Human FCER1G 187.2% Increase Gene Expression Level
DAA2274 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular hippocampus Human FCER1G 342.8% Increase Gene Expression Level
DAA2289 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular frontal lobe Human FCER1G 105.3% Increase Gene Expression Level
DAA2290 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular frontal lobe Human FCER1G 111.4% Increase Gene Expression Level
DAA2282 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular parietal lobe Human FCER1G 177.4% Increase Gene Expression Level
DAA2275 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular hippocampus Human FCER1G 222.6% Increase Gene Expression Level
DAA2270 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide increases with age Molecular temporal lobe Human FCER1G 98.1% Increase Gene Expression Level
DAA2283 Fc fragment of IgG binding protein increases with age Molecular parietal lobe Human FCGBP 290.6% Increase Gene Expression Level
DAA2291 Fc fragment of IgG binding protein increases with age Molecular frontal lobe Human FCGBP 212.4% Increase Gene Expression Level
DAA2276 Fc fragment of IgG binding protein increases with age Molecular hippocampus Human FCGBP 138.3% Increase Gene Expression Level
DAA2142 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular parietal lobe Human FCGR1A 207.6% Increase Gene Expression Level
DAA2140 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular hippocampus Human FCGR1A 423.1% Increase Gene Expression Level
DAA2138 Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age Molecular temporal lobe Human FCGR1A 151.0% Increase Gene Expression Level